MyBioSource.com's Anti-GRIA4 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Anti-GRIA4 Antibody was generated using GluA4, GluR4, and GRIA4 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Description: Rabbit IgG polyclonal antibody for Glutamate receptor 4(GRIA4) detection. Tested with WB in Human;Mouse;Rat.
Background: Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate (AMPA). Some haplotypes of this gene show a positive association with schizophrenia. What's more, glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels